Esophageal Cancer Modeling
The CISNET esophageal cancer group was formed in 2010 in the third round of CISNET funding with three distinct modeling teams focused on collaboratively modeling the incidence and mortality of esophageal adenocarcinoma (EAC) in the US population. The group’s work will include performing collaborative modeling of the natural history models of esophageal adenocarcinoma which will include precursor states such as Barrett’s esophagus and dysplasia that are calibrated to US SEER data.
The natural history models of EAC will serve as the platforms to perform analyses that evaluate prior and current screening and surveillance strategies, and preventions and interventions, such as endoscopic eradication therapies such as ablation.
The results from these research efforts will inform cancer control policies and also improve our understanding of the natural history of EAC.