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Principal Investigator:
Ann G. Zauber
Institution:
Sloan-Kettering Institute for Cancer Research
Grant Number: 1U01CA115953-01
Awarded under CA-05-018
Abstract: Population based microsimulation models can provide a sensitive
and informative tool for health policy to evaluate the population benefit and expenditures
for interventions to reduce the burden of colorectal cancer. However the value of such models
in the health policy area is often hampered by the uncertainty about what model outcomes
stand for and why they differ between models. This proposal is to coordinate the activities
of the investigators for the CISNET-Colon models to improve the dissemination of high quality
models and thereby enhance our ability to inform the important policy issues to reduce the
burden of colorectal cancer in the United States. A Clinical and Epidemiology Advisory Committee
will provide additional insights into addressing the important pertinent issues for colorectal
cancer. This proposal is from Memorial Sloan-Kettering Cancer Center in collaboration with
Erasmus University MC who has developed the MISCAN-Colon model as a participant for the CISNET-Colon
program. A multi-disciplinary team with experience in biostatistics, epidemiology, health
policy, and microsimulation modeling will address the following aims for the coordinating
center:
- To create an optimal environment for a fruitful cooperation within
the CISNET-Colon group.
- To formulate, prioritize and coordinate work on base case and other
questions within the CISNET-Colon group.
- To disseminate current policy-related issues and
the latest research results across the spectrum of prevention, screening and treatment
for colorectal cancer in order to facilitate access to the latest information in these
areas.
- To serve as a spokesperson, first contact and disseminator for requests
and collaborations from inside the CISNET groups and NCI, and from outside the CISNET-Colon
group.
- Work cooperatively
with the contractor, Lauren Clark of Cornerstone, who maintains the Model Profiler/Interactive
Web Site.
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