Recent Highlights: Gastric

Rising Concern: The CISNET Gastric Group Finds Young-Onset Gastric Cancer on the Rise Despite Global Decline

In this analysis, the Gastric group highlighted a concerning increase in young-onset gastric cancer since 2015, despite overall declining trends for gastric cancer globally. The findings underscore disparities based on sex and socio-demographic factors, which could inform targeted prevention strategies for younger populations.

Li Y, Hahn AI, Laszkowska M, Jiang F, Zauber AG, Leung WK. Global burden of young-onset gastric cancer: a systematic trend analysis of the global burden of disease study 2019. Gastric Cancer. 2024 Jul;27(4):684-700. doi: 10.1007/s10120-024-01494-6. Epub 2024 Apr 3. PMID: 38570392; PMCID: PMC11193827.

New Study by CISNET Gastric Group Highlights Similar Cancer Risks in Low and High-Risk Regions, Pointing to Need for Global Screening Guidelines

In a recent publication, members of the CISNET Gastric Group discovered that precursor lesions for gastric cancer progress at similar rates in both low and high-incidence regions. This suggests that surveillance strategies could be valuable even in low-risk areas, with significant implications for global cancer screening and prevention efforts.

Hahn AI, Mülder DT, Huang RJ, Zhou MJ, Blake B, Omofuma O, Murphy JD, Gutiérrez-Torres DS, Zauber AG, O'Mahony JF, Camargo MC, Ladabaum U, Yeh JM, Hur C, Lansdorp-Vogelaar I, Meester R, Laszkowska M. Global Progression Rates of Precursor Lesions for Gastric Cancer: A Systematic Review and Meta-Analysis. Clin Gastroenterol Hepatol. 2024 Oct 1:S1542-3565(24)00864-4. doi: 10.1016/j.cgh.2024.09.003. Epub ahead of print. PMID: 39362617.