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Past Highlights
Risk prediction models for selection of lung cancer screening participants: a retrospective validation study
ten Haaf K, Jeon J, Tammemägi MC, et al. Risk prediction models for selection of lung cancer screening participants: a retrospective validation study
. PLoS Medicine. 2017; 14(4): e1002277
Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012
Holford TR, Meza R, Warner KE et al. Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012. JAMA. 2014;311(2):164-171
Benefits and Harms of Computed Tomography Lung Cancer Screening Strategies: A Comparative Modeling Study for the U.S. Preventive Services Task Force
de Koning HJ, Meza R, Plevritis SK, et al. Benefits and Harms of Computed Tomography Lung Cancer Screening Strategies: A Comparative Modeling Study for the U.S. Preventive Services Task Force. Ann Intern Med, 2013
Patterns of Birth Cohort Specific Smoking Histories
Holford TR, Levy DT, McKay LA, et al. Patterns of Birth Cohort Specific Smoking Histories, 1965-2009. Am J Prev Med. 2014;46(2)
Impact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975-2000
Considerable effort has been expended on tobacco control strategies in the United States since the mid-1950s. However, we have little quantitative information on how changes in smoking behaviors have impacted lung cancer mortality. Impact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975-2000.
Lung Cancer Model Applied to Michigan and Kentucky to Measure Potential Impact of Tobacco Control Policies
CISNET members from the University of Michigan and Georgetown University used the SimSmoke model to project the potential effect of tobacco control policies on reducing smoking rates and on tobacco-related mortality in Michigan. The modelers worked closely with Michigan in-state partners to identify policies that could have a large impact on smoking rates and save lives in the state. Previous collaborations also helped to determine optimal tobacco control policies in Kentucky, the state with the highest adult smoking rates.
Results of these collaborative studies were published in the Cancer Causes and Control Journal and the Southern Medical Journal:
Levy DT, Huang A, Havumaki JS, Meza R. The Role of Public Policies in Reducing Smoking Prevalence: Results from the Michigan SimSmoke Tobacco Policy Simulation Model, Cancer Causes and Control 2016 May; 27(5):615-25. [Abstract]
Levy DT, Tworek C, Hahn EJ, Davis RE. 2008. The Kentucky SimSmoke tobacco policy simulation model: reaching Healthy People 2010 goals through policy change. South Med J 2008 May;101(5):503-7. [Abstract]
Read about related work in studying the effect of tobacco control programs.
CISNET Provides Support for Development of Lung Cancer Screening Guidelines
CISNET investigators collaborated with the US Preventive Services Task Force (USPSTF) to estimate the population benefits and harms of lung cancer screening in the US, evaluating the relative effectiveness of 576 alternative screening scenarios. The analyses supported the development of new lung cancer screening recommendations by the USPSTF (Moyer 2014; de Koning, Meza et al. 2014). Working with the USPSTF, CISNET investigators identified top-ranked scenarios that were determined to have an acceptable ratio of benefits and harms. According to the CISNET models, screening annually from ages 55-80 offers substantial benefits for individuals with at least 30 pack-years of exposure and no more than 15 years since quitting. These analyses provided additional evidence to support the recent USPSTF’s lung cancer screening guidelines, which gave low-dose CT screening a B recommendation (Moyer 2014).