CISNET Provides Support for Development of Lung Cancer Screening Guidelines

CISNET investigators collaborated with the US Preventive Services Task Force (USPSTF) to estimate the population benefits and harms of lung cancer screening in the US, evaluating the relative effectiveness of 576 alternative screening scenarios. The analyses supported the development of new lung cancer screening recommendations by the USPSTF (Moyer 2014; de Koning, Meza et al. 2014). Working with the USPSTF, CISNET investigators identified top-ranked scenarios that were determined to have an acceptable ratio of benefits and harms. According to the CISNET models, screening annually from ages 55-80 offers substantial benefits for individuals with at least 30 pack-years of exposure and no more than 15 years since quitting. These analyses provided additional evidence to support the recent USPSTF’s lung cancer screening guidelines, which gave low-dose CT screening a B recommendation (Moyer 2014).